Theme 3

Theme 3: New prognostic indicators

The newly established imaging options make it possible to follow large populations of patients over a prolonged period of time. By correlating image-derived measures to clinical events in this population, novel, imaging based prognostic indicators can be derived. In combination with more traditional risk factors (such as biochemical indicators), such indicators can be used for: 1) personalized early diagnosis, and 2) better prognostic estimates for improved patient management. The development of methods to derive these indicators is a new field of research. (Figure 4).

Figure 4: Imaging biomarkers which reflect the presence and state of carotid or coronary artery disease can be obtained with different imaging techniques, such as MRI, CT, and ultrasound. These imaging biomarkers may be indicative of rupture risk, and hence predictors of clinical events such as e.g. stroke.